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Contraception

Depo-Provera ("the shot")

What Is It?

Depo-Provera® is a progestin-only injectable contraceptive. It is an injection of the hormone progestin. It is administered every 3 months by  a medical provider.

How Does It Work?

Thickens cervical mucus, blocking sperm. Prevents ovulation. Prevents implantation of fertilized egg.

How Is It Used?

The woman is given an injection into the musle of the upper arm or buttocks or an injection into the fatty tissue of the abdomen or thigh every three months.

How Well Does It Work?

Typical use: 97%. Perfect use: 99.7%. Works for 12 weeks. Failure rate increased if shot is not repeated every 12 weeks.

What Are Its Main Advantages?

Lasts for 3 months. Does not interfere with sex. Can be used by women with a history of seizures (reduces seizures) or sickle cell anemia. Can be used while breastfeeding.

What Are Some Possible Problems? Need to return for shot every 3 months. Menstrual changes are common including: irregular bleeding, spotting, missed periods, or no periods. Side effects: weight gain, depression, breast tenderness, headaches, allergic reaction. Side effects may last for up to 6 months after the last injection. May cause delay in ability to get pregnant after discontinuation. May cause bone density changes or bone loss; adverse effects on lipids.

Warning

BLACK BOX WARNING:  Women who use DMPA may lose significant bone mineral density.  Bone loss is greater with increasing duration of use and may not be completely reversible.  It is unknown if use of DMPA during adolescence or early adulthood, a critical period of bone accretion, will reduce peak bone mass and increase the risk for osteoporotic fracture in later life.  DMPA should be used as a long-term birth control method (e.g., longer than 2 years) only if other birth control methods are inadequate.

 

Source: Contraceptive Technology: Seventeenth Revised Edition, Hatcher RA, Trussel J., et al., New York, NY; Irvington Publishers, 1998.

 

 

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